Murray valley encephalitis virus envelope protein antigenic variants with altered hemagglutination properties and reduced neuroinvasiveness in mice.

doi:10.1006/viro.1995.1374

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Article

Murray valley encephalitis virus envelope protein antigenic variants with altered hemagglutination properties and reduced neuroinvasiveness in mice.

Virology - 1 Aug 1995

McMinn P C, Lee E, Hartley S, Roehrig J T, Dalgarno L, Weir R C

Abstract excerpt

Neutralization escape variants of Murray Valley encephalitis virus were selected using a type-specific, neutralizing, and passively protective anti-envelope protein (E) monoclonal antibody (4B6C-2) which defines epitope E-1c. Nucleotide sequence analysis revealed single nucleotide changes in the E genes of 15 variants resulting in nonconservative amino acid substitutions in all cases. One variant had a...

Topics

Amino Acid Sequence
Animals
Base Sequence
Brain
Chlorocebus aethiops
Codon
Encephalitis Virus, Murray Valley
Encephalitis, Arbovirus
Enzyme-Linked Immunosorbent Assay
Erythrocytes
Geese

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Hemagglutination Tests

Hemagglutinins, Viral

Mice

Point Mutation

Sequence Deletion

Vero Cells

Source

Open in PubMed

Identifiers

PMID: 7645203
DOI: 10.1006/viro.1995.1374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7645203-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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