Article
Envelope protein glycosylation status influences mouse neuroinvasion phenotype of genetic lineage 1 West Nile virus strains.
Journal of virology - 1 Jul 2005
Beasley David W C, Whiteman Melissa C, Zhang Shuliu, Huang Claire Y-H, Schneider Bradley S, Smith Darci R, Gromowski Gregory D, Higgs Stephen, Kinney Richard M, Barrett Alan D T
Abstract excerpt
The introduction of West Nile virus (WNV) into North America has been associated with relatively high rates of neurological disease and death in humans, birds, horses, and some other animals. Previous studies identified strains in both genetic lineage 1 and genetic lineage 2, including North American isolates of lineage 1, that were highly virulent in a mouse neuroinvasion model, while other strains were...
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