A mouse-attenuated envelope protein variant of Murray Valley encephalitis virus with altered fusion activity.

doi:10.1099/0022-1317-77-9-2085

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Article

A mouse-attenuated envelope protein variant of Murray Valley encephalitis virus with altered fusion activity.

The Journal of general virology - 1 Sept 1996

McMinn P C, Weir R C, Dalgarno L

Abstract excerpt

A neutralization escape variant of Murray Valley encephalitis virus (MVE), of low neuroinvasiveness in mice and with low haemagglutination activity, had a reduced rate of replication in cultured cells during the early phase of infection compared to wild-type MVE. The variant was internalized by V...

Topics

Aedes
Animals
Antibodies, Monoclonal
Antibodies, Viral
Cell Line
Chlorocebus aethiops
Encephalitis Virus, Murray Valley
Genetic Variation
Membrane Fusion
Mice
Vero Cells
Viral Envelope Proteins
Virus Replication

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