Article
A mouse-attenuated envelope protein variant of Murray Valley encephalitis virus with altered fusion activity.
The Journal of general virology - 1 Sept 1996
McMinn P C, Weir R C, Dalgarno L
Abstract excerpt
A neutralization escape variant of Murray Valley encephalitis virus (MVE), of low neuroinvasiveness in mice and with low haemagglutination activity, had a reduced rate of replication in cultured cells during the early phase of infection compared to wild-type MVE. The variant was internalized by Vero cells at a similar rate to wild-type MVE at pH 7.4, but had reduced pH-dependent membrane fusion activity. In...
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