c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas.

doi:10.1074/jbc.270.32.18961

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Article

c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas.

The Journal of biological chemistry - 11 Aug 1995

Chou T Y, Hart G W, Dang C V

Abstract excerpt

c-Myc is a helix-loop leucine zipper phosphoprotein that heterodimerizes with Max and regulates gene transcription in cell proliferation, cell differentiation, and programmed cell death. Previously, we demonstrated that c-Myc is modified by O-linked N-acetylglucosamine (O-GlcNAc) within or nearby...

Topics

Amino Acid Sequence
Animals
Glycosylation
Lymphoma
Molecular Sequence Data
Mutation
Phosphorylation
Proto-Oncogene Proteins c-myc
Recombinant Proteins
Spodoptera
Threonine

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