Article
Function of the c-Myc oncoprotein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 1992
Kato G J, Dang C V
Abstract excerpt
The c-Myc protein, the product of the c-myc proto-oncogene, is a nuclear phosphoprotein with DNA binding properties. Deregulated c-myc expression participates in the development of experimentally induced tumors, and its expression appears to be abnormal in many naturally occurring malignancies. Although the precise molecular mechanism of c-Myc activity in oncogenesis and in normal cell proliferation is unknown,...
Topics
- Animals
- Humans
- Phenotype
- Proto-Oncogene Mas
- Proto-Oncogene Proteins c-myc
