Identification of an inhibitory domain of CTP:phosphocholine cytidylyltransferase.

doi:10.1074/jbc.270.32.18948

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Article

Identification of an inhibitory domain of CTP:phosphocholine cytidylyltransferase.

The Journal of biological chemistry - 11 Aug 1995

Wang Y, Kent C

Abstract excerpt

The function of the putative amphipathic helices between residues 236 and 314 of CTP:phosphocholine cytidylyltransferase was examined by constructing two truncation mutants; CT314 was missing the entire phosphorylation segment, whereas CT236 was missing both the region with the putative amphipath...

Topics

Animals
Base Sequence
CHO Cells
Choline-Phosphate Cytidylyltransferase
Cricetinae
Enzyme Activation
Molecular Sequence Data
Mutation
Nucleotidyltransferases
Phosphorylation
Structure-Activity Relationship

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