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Article

Functions of membrane binding domain of CTP:phosphocholine cytidylyltransferase in alveolar type II cells.

American journal of respiratory cell and molecular biology - 1 Jul 2010

Ridsdale Ross, Tseu Irene, Wang Jinxia, Post Martin

Abstract excerpt

CTP:phosphocholine cytidylyltransferase (CCTalpha) plays a key role in the biosynthesis of surfactant phosphatidylcholine. In this study, we investigated the role of its membrane-binding (M) domain in modulating its structure, function, and cellular distribution. Multiple enhanced green fluorescent protein-CCTalpha constructs were generated to evaluate the subcellular distribution in A549 cells. The M domain...

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Identifiers

PMID: 19684306
DOI: 10.1165/rcmb.2009-0231OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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