Article
Alternative splicing of the human alpha 2(VI) collagen gene generates multiple mRNA transcripts which predict three protein variants with distinct carboxyl termini.
The Journal of biological chemistry - 15 Apr 1990
Saitta B, Stokes D G, Vissing H, Timpl R, Chu M L
Abstract excerpt
We recently reported the isolation and sequencing of two classes of human alpha 2(VI) collagen cDNA clones which share common sequences for the first two-thirds of the molecule but contain a different sequence of either 607 or 887 base pairs at their 3' ends (Chu, M.-L., Pan, T.-C., Conway, D., K...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Northern
- Cell Line
- Collagen
- DNA
- Genes
- Genetic Variation
- Humans
- Molecular Sequence Data
- Oligonucleotide Probes
- RNA
- RNA Splicing
- RNA, Messenger
- Restriction Mapping
- Transcription, Genetic