Article
Comparison of growth rate of two B16 melanomas differing in metastatic potential in young versus middle-aged mice.
Cancer investigation - 1 Jan 1997
Donin N, Sinai J, Staroselsky A, Mahlin T, Nordenberg J, Leibovici J
Abstract excerpt
The rise of cancer frequency as a function of age is a well-established fact. The aspect of the host age-tumor progression relationship, namely the slower metastatic spread in aged patients, has been investigated to a lesser extent. In the present study, we examined whether host-age-dependent growth rate varies with metastatic capacity of the tumor. The parental B16 and the B16/Col/R, a highly metastatic variant,...
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