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Article

Involvement of protein-DNA interaction in adeno-associated virus Rep78-mediated inhibition of HIV-1.

Journal of human virology - 1 Jan 2000

Kokorina N A, Santin A D, Li C, Hermonat P L

Abstract excerpt

OBJECTIVE: It has been well documented by several laboratories that adeno-associated virus (AAV) is able to inhibit HIV-1 replication and gene expression. This effect has been mapped to the AAV-encoded Rep78 protein. However, the mechanism by which Rep78 is able to inhibit HIV-1 is unclear. As Rep78 is a DNA binding transcription factor, the objective of this study was to investigate where Rep78 might bind within...

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Share to Dependovirus
Share to DNA, Viral
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Long Terminal Repeat

Share to TATA Box

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Source

Identifiers

PMID: 10195265

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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