The role of Hoxa-3 in mouse thymus and thyroid development.

doi:10.1242/dev.121.7.1989

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Article

The role of Hoxa-3 in mouse thymus and thyroid development.

Development (Cambridge, England) - 1 Jul 1995

Manley N R, Capecchi M R

Abstract excerpt

Targeted disruption of Hoxa-3 results in a number of regionally restricted defects in tissues and structures derived from or patterned by mesenchymal neural crest. However, analysis of mutant embryos with injections of a carbocyanine dye or with molecular markers that label these cells indicates that neither the amount nor the migration patterns of this neural crest population are grossly affected. Therefore, it...

Topics

Animals
Base Sequence
DNA Primers
Fluorescent Antibody Technique
Gene Expression
Genes, Homeobox
Homeodomain Proteins
In Situ Hybridization
Mesoderm
Mice
Mice, Mutant Strains
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Morphogenesis

Neural Crest

Phenotype

Thymus Gland

Thyroid Gland

Source

Open in PubMed

Identifiers

PMID: 7635047
DOI: 10.1242/dev.121.7.1989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7635047-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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