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Article

Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis.

Developmental biology - 15 Aug 2001

Su D, Ellis S, Napier A, Lee K, Manley N R

Abstract excerpt

The thymus and parathyroid glands in mice develop from a thymus/parathyroid primordium that forms from the endoderm of the third pharyngeal pouch. We investigated the molecular mechanisms that promote this unique process in which two distinct organs form from a single primordium, using mice mutant for Hoxa3 and Pax1. Thymic ectopia in Hoxa3(+/-)Pax1(-/-) compound mutants is due to delayed separation of the...

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PMID: 11476574
DOI: 10.1006/dbio.2001.0342

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Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis.PMID 11476574Read ↗

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