Article
Immunoprinting: various genes are associated with increased risk to develop rheumatoid arthritis in different groups of adult patients.
Journal of molecular medicine (Berlin, Germany) - 1 Jan 1995
Gomolka M, Menninger H, Saal J E, Lemmel E M, Albert E D, Niwa O, Epplen J T, Epplen C
Abstract excerpt
To identify genes that contribute to the manifestation of rheumatoid arthritis we performed association studies via microsatellite analyses of immunorelevant loci (HLA-DRB, 5 T cell receptor loci, TNFa IL1, IL2, IL5R and CD40L). A total of 183 patients and 275 healthy controls were typed in terms of HLA and grouped according to the known predisposing HLA-DRB1 genes (DRB1*04; relative risk approx. 5; DRB1*01,...
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