Article
Immunoprinting excludes many potential susceptibility genes as predisposing to early onset pauciarticular juvenile chronic arthritis except HLA class II and TNF.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1995
Epplen C, Rumpf H, Albert E, Haas P, Truckenbrodt H, Epplen J T
Abstract excerpt
DNA profiles (immunoprints) were generated for 120 patients suffering from early onset pauciarticular chronic arthritis (EOPA-JCA) and > 500 healthy controls utilizing highly polymorphic microsatellites in the vicinity of immunorelevant genes. Six T cell receptor (TCR) markers for the CD3D, TCRDV...
Topics
- Age of Onset
- Antigens, CD
- Arthritis, Juvenile
- Autoimmune Diseases
- Base Sequence
- Child, Preschool
- Cytokines
- DNA Fingerprinting
- Disease Susceptibility
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- HLA Antigens
- HLA-D Antigens