Article
Complex genetic predisposition in adult and juvenile rheumatoid arthritis.
BMC genetics - 4 Feb 2004
Miterski Bianca, Drynda Susanne, Böschow Gundula, Klein Wolfram, Oppermann Joachim, Kekow Jörn, Epplen Jörg Thomas
Abstract excerpt
BACKGROUND: Rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) are complex multifactorial diseases caused by environmental influences and an unknown number of predisposing genes. The present study was undertaken in order to investigate association of polymorphisms in candidate genes with RA and JRA in German subjects. RESULTS: Up to 200 unrelated German RA and JRA patients each and 300-400 healthy...
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