Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The somatic hypermutation activity of a follicular lymphoma links to large insertions and deletions of immunoglobulin genes.

Scandinavian journal of immunology - 1 Jul 1995

Wu H Y, Kaartinen M

Abstract excerpt

A biopsy specimen from a patient with follicular lymphoma was divided into two fragments. DNA was extracted from one fragment and a 1.2 kb region of the functional heavy chain (IgH) gene was amplified, cloned and sequenced (eight clones). From the other fragment a cell line (HF-1) was started. The IgH gene region was amplified from the cell line, and sequenced without cloning. The nine sequences obtained could be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Gene Deletion
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Polymorphism, Genetic

Share to Selection, Genetic

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 7631145
DOI: 10.1111/j.1365-3083.1995.tb03625.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The somatic hypermutation activity of a follicular lymphoma links to large insertions and deletions of immunoglobulin genes.PMID 7631145Read ↗

A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro.Semantic proximity Read ↗

Somatic hypermutations in the immunoglobulin genes of two new human lymphoma lines of lymphatic follicle origin.Semantic proximity Read ↗

High Throughput Sequencing Analysis of the Immunoglobulin Heavy Chain Gene from Flow-Sorted B Cell Sub-Populations Define the Dynamics of Follicular Lymphoma Clonal Evolution.Semantic proximity Read ↗

The genetic variability of the VH genes in follicular lymphoma: the impact of the hypermutation mechanism.Semantic proximity Read ↗

Distribution and nucleotide biases of the somatic hypermutations in the functional kappa light chain gene of a human follicular lymphoma line.Semantic proximity Read ↗

Clonal expansion in follicular lymphoma occurs subsequent to antigenic selection.Semantic proximity Read ↗

Somatic hypermutation of immunoglobulin variable region genes: focus on follicular lymphoma and multiple myeloma.Semantic proximity Read ↗

New type of t(14;18) in a non-Hodgkin's lymphoma provides insight in molecular events in early B-cell differentiation.Semantic proximity Read ↗

Classical Hodgkin's disease and follicular lymphoma originating from the same germinal center B cell.Semantic proximity Read ↗

[Progress in the research of gene mutations in follicular lymphoma].Semantic proximity Read ↗

Clonal evolution in a primary cutaneous follicle center B cell lymphoma revealed by single cell analysis in sequential biopsies.Semantic proximity Read ↗

Cell migration patterns and ongoing somatic mutations in the progression of follicular lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.