Article
New type of t(14;18) in a non-Hodgkin's lymphoma provides insight in molecular events in early B-cell differentiation.
British journal of haematology - 1 Nov 1995
Meijerink J P, Raemaekers J M, Mensink E J
Abstract excerpt
In this report a follicular non-Hodgkin's lymphoma (NHL) carrying an unusual t(14;18) is described. This translocation most likely occurred during the VH to D-JH rearrangement process of the IgH locus. From the data combined with data from the literature we conclude that the chance for developmen...
Topics
- Adult
- B-Lymphocytes
- Base Sequence
- Cell Differentiation
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 18
- Gene Rearrangement
- Humans
- Lymphoma, Non-Hodgkin
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-bcl-2
- Translocation, Genetic
