Article
New type of t(14;18) in a non-Hodgkin's lymphoma provides insight in molecular events in early B-cell differentiation.
British journal of haematology - 1 Nov 1995
Meijerink J P, Raemaekers J M, Mensink E J
Abstract excerpt
In this report a follicular non-Hodgkin's lymphoma (NHL) carrying an unusual t(14;18) is described. This translocation most likely occurred during the VH to D-JH rearrangement process of the IgH locus. From the data combined with data from the literature we conclude that the chance for development of a t(14;18) decreases during progression of the immunoglobulin rearrangement process in the pre-B-cell ontogeny....
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