Article
Classical Hodgkin's disease and follicular lymphoma originating from the same germinal center B cell.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Dec 1999
Marafioti T, Hummel M, Anagnostopoulos I, Foss H D, Huhn D, Stein H
Abstract excerpt
PURPOSE: Classical Hodgkin's disease and non-Hodgkin's B-cell lymphoma occasionally occur in the same patient. To clarify whether these different diseases share a common precursor cell, we analyzed the immunoglobulin rearrangements in tumor cells of the classical Hodgkin's disease and the follicular lymphoma that developed in the same patient 2 years apart. PATIENTS AND METHODS: Polymerase chain reaction (PCR)...
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