Cell-cycle checkpoints. Keeping mitosis in check.

doi:10.1016/s0960-9822(95)00077-7

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Article

Cell-cycle checkpoints. Keeping mitosis in check.

Current biology : CB - 1 Apr 1995

Humphrey T, Enoch T

Abstract excerpt

Mutations in an essential yeast gene, encoding DNA polymerase epsilon, abolish the dependence of mitosis on the completion of DNA replication, suggesting that the replication complex provides the checkpoint signal.

Topics

Animals
DNA Polymerase II
DNA Replication
DNA-Directed DNA Polymerase
Humans
Mitosis
Mutation
Saccharomyces cerevisiae
Schizosaccharomyces

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