Article
DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability.
Molecular cell - 1 May 1999
Kesti T, Flick K, Keränen S, Syväoja J E, Wittenberg C
Abstract excerpt
DNA polymerase epsilon (Pol epsilon) is believed to play an essential catalytic role during eukaryotic DNA replication and is thought to participate in recombination and DNA repair. That Pol epsilon is essential for progression through S phase and for viability in budding and fission yeasts is a central element of support for that view. We show that the amino-terminal portion of budding yeast Pol epsilon (Pol2)...
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