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Article

A screen for dominant modifiers of the irreC-rst cell death phenotype in the developing Drosophila retina.

Genetics - 1 Sept 2000

Tanenbaum S B, Gorski S M, Rusconi J C, Cagan R L

Abstract excerpt

Programmed cell death (PCD) in the Drosophila retina requires activity of the irregular chiasmC-roughest (irreC-rst) gene. Loss-of-function mutations in irreC-rst block PCD during retinal development and lead to a rough eye phenotype in the adult. To identify genes that interact with irreC-rst and may be involved in PCD, we conducted a genetic screen for dominant enhancers and suppressors of the adult rough eye...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10978286
DOI: 10.1093/genetics/156.1.205
PMCID: PMC1461222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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