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Article

The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila.

Cell death and differentiation - 1 Oct 2006

Xu D, Wang Y, Willecke R, Chen Z, Ding T, Bergmann A

Abstract excerpt

Caspases are essential components of the apoptotic machinery in both vertebrates and invertebrates. Here, we report the isolation of a mutant allele of the Drosophila effector caspase drICE as a strong suppressor of hid- (head involution defective-) induced apoptosis. This mutant was used to determine the apoptotic role of drICE. Our data are consistent with an important function of drICE for developmental and...

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Identifiers

PMID: 16645642
DOI: 10.1038/sj.cdd.4401920
PMCID: PMC2519037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila.PMID 16645642Read ↗

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