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Article

A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila.

Genetics - 1 Sept 2008

Wang Lei, Evans Janelle, Andrews Hillary K, Beckstead Robert B, Thummel Carl S, Bashirullah Arash

Abstract excerpt

The steroid hormone ecdysone triggers the rapid and massive destruction of larval tissues through transcriptional cascades that culminate in rpr and hid expression and caspase activation. Here we describe the use of genetic screens to further our understanding of this steroid-triggered programmed cell death response. Pupal lethal mutants were screened for specific defects in larval salivary gland destruction. A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18757938
DOI: 10.1534/genetics.108.092478
PMCID: PMC2535680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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