Article
Rescue of the fission yeast snRNA synthesis mutant snm1 by overexpression of the double-strand-specific Pac1 ribonuclease.
Molecular & general genetics : MGG - 25 Jun 1995
Rotondo G, Gillespie M, Frendewey D
Abstract excerpt
The Schizosaccharomyces pombe temperature-sensitive mutant snm1 maintains reduced steady-state quantities of the spliceosomal small nuclear RNAs (snRNAs) and the RNA subunit of the tRNA processing enzyme RNase P. We report here the isolation of the pac1+ gene as a multi-copy suppressor of snm1. T...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA-Binding Proteins
- Endodeoxyribonucleases
- Endoribonucleases
- Fungal Proteins
- Genes, Suppressor
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- RNA, Double-Stranded