Article
Genes for a nuclease and a protease are involved in the drastic decrease in cellular RNA amount in fission yeast cells during nitrogen starvation.
Journal of biochemistry - 1 Mar 2002
Nakashima Akio, Yoshida Mayumi, Nakayama Kazutoshi, Kato-Furuno Aya, Ueno Masaru, Ushimaru Takashi, Uritani Masahiro
Abstract excerpt
Cellular RNA in Schizosaccharomyces pombe cells drastically decreases in amount during nitrogen starvation. Previously, we found and purified a soluble RNA-degrading enzyme whose activity drastically increased in the cells of S. pombe undergoing nitrogen starvation. The enzyme was a nuclease encoded by pnu1(+). In this study, the increase in the RNA-degrading activity and the decrease in cellular RNA level are...
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