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Article

S. pombe pac1+, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase.

The EMBO journal - 1 Jan 1991

Iino Y, Sugimoto A, Yamamoto M

Abstract excerpt

The Schizosaccharomyces pombe pac1 gene is a multicopy suppressor of the pat1 temperature-sensitive mutation, which directs uncontrolled meiosis at the restrictive temperature. Overexpression of the pac1 gene had no apparent effect on vegetative growth but inhibited mating and sporulation in wild type S. pombe cells. In such cells, expression of certain genes required for mating or meiosis was inhibited. The pac1...

Topics

Amino Acid Sequence
Base Sequence
Endoribonucleases
Escherichia coli Proteins
Gene Expression
Genes, Fungal
Genotype
Meiosis
Molecular Sequence Data
Restriction Mapping
Ribonuclease III

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizosaccharomyces

Sequence Homology, Nucleic Acid

Spores, Fungal

Source

Open in PubMed Open full text

Identifiers

PMID: 1989884
DOI: 10.1002/j.1460-2075.1991.tb07939.x
PMCID: PMC452633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1989884-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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