Article
Loss of Drosophila Myb interrupts the progression of chromosome condensation.
Nature cell biology - 1 May 2007
Manak J Robert, Wen Hong, Van Tran, Andrejka Laura, Lipsick Joseph S
Abstract excerpt
Completion of chromosome condensation is required before segregation during the mitotic cell cycle to ensure the transmission of genetic material with high fidelity in a timely fashion. In many eukaryotes this condensation is regulated by phosphorylation of histone H3 on Ser 10 (H3S10). This phosphorylation normally begins in the late-replicating pericentric heterochromatin and then spreads to the earlier...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
