Article
Microsatellite instability in colorectal cancer: improved assessment using fluorescent polymerase chain reaction.
Gastroenterology - 1 Aug 1995
Cawkwell L, Li D, Lewis F A, Martin I, Dixon M F, Quirke P
Abstract excerpt
BACKGROUND & AIMS: Microsatellite instability was first described in hereditary nonpolyposis colorectal cancers and sporadic colorectal cancers, in which it was associated with a good prognosis. The aim of this study was to assess the advantages of a novel fluorescent assay for detecting microsat...
Topics
- Adenocarcinoma
- Aged
- Alleles
- Colorectal Neoplasms
- DNA, Satellite
- Female
- Fluorescence
- Humans
- Image Interpretation, Computer-Assisted
- Polymerase Chain Reaction
- Prognosis
