Article
Frequency of microsatellite instability inBreast cancer determined by high-resolution fluorescent microsatellite analysis.
Oncology - 1 Jun 2000
Tokunaga E, Oki E, Oda S, Kataoka A, Kitamura K, Ohno S, Maehara Y, Sugimachi K
Abstract excerpt
In breast cancer, the rates of positivity for microsatellite instability (MSI), vary greatly in the literature. Using high-resolution fluorescent microsatellite analysis (HFRMA), we studied microsatellite alterations in 75 patients with sporadic breast cancer. In this system, several devices were prepared to improve reproducibility of polymerase chain reaction products, migration accuracy of electrophoresis, and...
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