Article
Dissociation of seizure traits in inbred strains of mice using the flurothyl kindling model of epileptogenesis.
Experimental neurology - 1 Jan 2009
Papandrea Dominick, Anderson Tara M, Herron Bruce J, Ferland Russell J
Abstract excerpt
Previous seizure models have demonstrated genetic differences in generalized seizure threshold (GST) in inbred mice, but the genetic control of epileptogenesis is relatively unexplored. The present study examined, through analysis of inbred strains of mice, whether the seizure characteristics observed in the flurothyl kindling model are under genetic control. Eight consecutive, daily generalized seizures were...
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