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Article

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors.

Journal of virology - 1 Aug 1995

van den Broek M F, Müller U, Huang S, Aguet M, Zinkernagel R M

Abstract excerpt

Alpha/beta interferon (IFN) and gamma IFN exert widely overlapping biological effects. Still, mice with individually inactivated alpha/beta or gamma receptors exhibit variably severely reduced resistance to infection and altered immune responses. To investigate to what extent the two IFN systems...

Topics

Animals
Female
Immunity, Cellular
Lymphocytic Choriomeningitis
Lymphocytic choriomeningitis virus
Male
Membrane Proteins
Mice
Phenotype
Receptor, Interferon alpha-beta
Receptors, Interferon
Spodoptera

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

T-Lymphocytes, Cytotoxic

Vaccinia

Vaccinia virus

Interferon gamma Receptor

Source

Open in PubMed Open full text

Identifiers

PMID: 7609046
DOI: 10.1128/JVI.69.8.4792-4796.1995
PMCID: PMC189290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7609046-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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