Article
Stimulation of basal transcription from the mouse mammary tumor virus promoter by Oct proteins.
Journal of virology - 1 Aug 1995
Kim M H, Peterson D O
Abstract excerpt
The steroid hormone-inducible promoter of mouse mammary tumor virus (MMTV) contains three overlapping sequences related to the consensus octamer motif ATGCAAAT. Basal promoter activity in the absence of hormone induction from a template in which all three octamer elements were mutated was decreased by two-to threefold in in vitro transcription assays. Oct-1 protein purified from HeLa cell nuclear extracts, as...
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