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Article

A novel transcriptional activator (PO-B) binds between the TATA box and cap site of the pro-opiomelanocortin gene.

Nucleic acids research - 11 Aug 1990

Riegel A T, Remenick J, Wolford R G, Berard D S, Hager G L

Abstract excerpt

We demonstrate that a factor (PO-B), detected in a number of mammalian cell lines, binds specifically between the TATA box and the transcription initiation site of the pituitary-specific pro-opiomelanocortin (POMC) gene. Methylation interference and DNAse 1 footprint analysis revealed that the binding site of this protein, -3 to -15, does not overlap the POMC TATA box or cap site. Mutation of the PO-B binding...

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Source

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Identifiers

PMID: 2388831
DOI: 10.1093/nar/18.15.4513
PMCID: PMC331272

Genes

POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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