Article
Two independent pathways for transcription from the MMTV promoter.
The Journal of steroid biochemistry and molecular biology - 1 Oct 1994
Möws C C, Preiss T, Slater E P, Cao X, Verrijzer C P, van Der Vliet P C, Beato M
Abstract excerpt
The influence of progesterone receptor (PR) and glucocorticoid receptor (GR) on transcription from the mouse mammary tumour virus (MMTV) promoter was analyzed using cell-free transcription of DNA templates with a G-free cassette. Preincubation of the templates with either PR or GR stimulates the rate of transcription initiation 10-50 fold, whereas the recombinant DNA binding domain of GR is inactive. Mutations...
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