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Article

Segregation analysis of HDL cholesterol in the NHLBI Family Heart Study and in Utah pedigrees.

European journal of human genetics : EJHG - 1 Jun 2002

Kronenberg Florian, Coon Hilary, Ellison R Curtis, Borecki Ingrid, Arnett Donna K, Province Michael A, Eckfeldt John H, Hopkins Paul N, Hunt Steven C

Abstract excerpt

We investigated the genetic determination of high-density-lipoprotein cholesterol (HDL-C) levels in the NHLBI Family Heart Study by segregation analysis. Included was a total of 3755 subjects from 560 randomly selected nuclear families and 522 families selected due to a high family risk of coronary heart disease (CHD). In the whole dataset, there was no evidence for an allele at a major gene locus responsible for...

Topics

Alleles
Cholesterol, HDL
Chromosome Mapping
Female
Humans
Hyperlipoproteinemia Type II
Male
Middle Aged
Pedigree
Triglycerides
Utah

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12080388
DOI: 10.1038/sj.ejhg.5200818

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