Article
Segregation analysis of drinking problem in elderly men and their first-degree relatives from the Western Collaborative Group Study.
Annals of epidemiology - 1 Jul 2000
Cheng L S, Carmelli D, Swan G E, Pfefferbaum A
Abstract excerpt
PURPOSE: The purpose of this study is to determine the mode of inheritance of alcohol-related drinking problems. METHODS: Family history was collected by interview from 493 elderly male participants (probands) in a follow-up cardiovascular exam of healthy white men living in the San Francisco Bay Area and Los Angeles. Segregation analysis was used to test for the presence of a major gene effect underlying the...
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