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Article

Determinants of plasma platelet-activating factor acetylhydrolase: heritability and relationship to plasma lipoproteins

1 Nov 1997

Abstract excerpt

Plasma platelet-activating factor acetylhydrolase (PAF-AH) is the enzyme that inactivates PAF (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine). We determined the relative contributions of genetic and environmental factors to variation in plasma PAF-AH activity in 240 individuals from 60 nuclear families. Regression of mean-offspring PAF-AH activity on the mid-parent value indicated that 62% of the variation in...

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PMID: 9392426
DOI: 10.1016/s0022-2275(20)34942-7

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