Article
Lipoprotein(a) in homozygous familial hypercholesterolemia.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2000
Kraft H G, Lingenhel A, Raal F J, Hohenegger M, Utermann G
Abstract excerpt
Lipoprotein(a) [Lp(a)] is a quantitative genetic trait that in the general population is largely controlled by 1 major locus-the locus for the apolipoprotein(a) [apo(a)] gene. Sibpair studies in families including familial defective apolipoprotein B or familial hypercholesterolemia (FH) heterozygotes have demonstrated that, in addition, mutations in apolipoprotein B and in the LDL receptor (LDL-R) gene may affect...
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