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Article

[Aging and immortalization of human cells].

Human cell - 1 Dec 1994

Naniwa M, Kano Y, Iijima M, Kondo T, mihara K

Abstract excerpt

In vitro models of malignant transformation of human cells may provide considerable insight into the mechanisms of multistep carcinogenesis. It is well established that normal human cells must be immortalized before they are malignantly transformed, but normal human cells are extremely refractory to immortalization, making malignant transformation very difficult. Thus immortalization is a rate-limiting step in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 7599106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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