Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck.

British journal of cancer - 1 Jul 1995

Kiaris H, Spandidos D A, Jones A S, Vaughan E D, Field J K

Abstract excerpt

Mutation and overexpression are the main activating mechanisms for the ras family of genes in human cancer and the variable tandem repeat (VTR) located at the 3' end of H-ras has been associated with this risk. In the present study, we have analysed the relative levels of expression of H-ras mRNA in 26 samples of squamous cell carcinomas of the head and neck (SCCHN) by competitive reverse transcription-polymerase...

Topics

Base Sequence
Carcinoma, Squamous Cell
Gene Expression Regulation, Neoplastic
Genes, ras
Head and Neck Neoplasms
Humans
Molecular Sequence Data
Mutation
Proto-Oncogene Mas
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repetitive Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 7599040
DOI: 10.1038/bjc.1995.287
PMCID: PMC2034114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7599040-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck.PMID 7599040Read ↗

Prevalence of RAS oncogene mutation in head and neck carcinomas.Semantic proximity Read ↗

Analysis of the c-Ha-ras-1 gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas.Semantic proximity Read ↗

Analysis of ras oncogene mutations in human squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

MUTATIONS OF RAS GENES IN HUMAN TUMORS (REVIEW)Semantic proximity Read ↗

The ras oncogenes in human lung cancer.Semantic proximity Read ↗

High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India.Semantic proximity Read ↗

Low incidence of ras oncogene activation in human squamous cell carcinomas.Semantic proximity Read ↗

The absence of Harvey ras mutations during development and progression of squamous cell carcinomas of the head and neck.Semantic proximity Read ↗

Low incidence of point mutation at codon 12 of K-ras proto-oncogene in squamous cell carcinoma of the upper aerodigestive tract.Semantic proximity Read ↗

Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines.Semantic proximity Read ↗

ras mutations and expression in head and neck squamous cell carcinomas.Semantic proximity Read ↗

Ras mutations in United Kingdom examples of oral malignancies are infrequent.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.