Article
Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck.
British journal of cancer - 1 Jul 1995
Kiaris H, Spandidos D A, Jones A S, Vaughan E D, Field J K
Abstract excerpt
Mutation and overexpression are the main activating mechanisms for the ras family of genes in human cancer and the variable tandem repeat (VTR) located at the 3' end of H-ras has been associated with this risk. In the present study, we have analysed the relative levels of expression of H-ras mRNA in 26 samples of squamous cell carcinomas of the head and neck (SCCHN) by competitive reverse transcription-polymerase...
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