Article
ras mutations and expression in head and neck squamous cell carcinomas.
The Laryngoscope - 1 Nov 1994
Yarbrough W G, Shores C, Witsell D L, Weissler M C, Fidler M E, Gilmer T M
Abstract excerpt
Mutational activation and overexpression of the family of ras proto-oncogenes have been associated with many human tumors. The role of mutations of H-ras, K-ras, and N-ras, as well as expression of the respective protein products (p21s) in normal mucosa, dysplastic mucosa, and squamous cell carci...
Topics
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Squamous Cell
- Codon
- DNA, Neoplasm
- Exons
- Fibrosarcoma
- Gene Amplification
- Gene Expression Regulation, Neoplastic
- Genes, ras
- Head and Neck Neoplasms
- Humans
- Lymphatic Metastasis
- Middle Aged
- Mutation
- Oligonucleotides
- Oncogene Protein p21(ras)