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Article

Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines.

Odontology - 1 Jul 2012

Maemoto Sachiko, Yumoto Megumi, Ibata Masato, Torizuka Sho, Ozawa Naohumi, Tatsumi Shunsuke, Hashido Moeko, Morikawa Masako, Maeda Genta, Imai Kazushi

Abstract excerpt

RAS overexpression and its active mutations are involved in malignant tumorigenesis. However, the mutation rates in oral carcinoma cells differ between populations. In the present study, genomic DNA of oral carcinoma cells (HOC313, TSU, HSC2, HSC3, KOSC2, KOSC3, SCCKN, OSC19, Ca9.22, and Ho1u1 cells) or normal gingival fibroblasts (GF12 cells) derived from a Japanese population were amplified by polymerase chain...

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Identifiers

PMID: 21607592
DOI: 10.1007/s10266-011-0032-3

Genes

HRAS
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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