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Article

Tumour necrosis factors and several interleukins inhibit the growth and modulate the antigen expression of normal human melanocytes in vitro.

Archives of dermatological research - 1 Jan 1995

Krasagakis K, Garbe C, Eberle J, Orfanos C E

Abstract excerpt

In the present study the action of various cytokines as regulators of human melanocyte growth and differentiation was examined in vitro. Primary melanocyte cultures were obtained in complete medium free of 12-O-tetradecanoylphorbol-13-acetate or serum. First passage melanocytes were treated with various concentrations of recombinant tumour necrosis factor alpha and beta (rTNF-alpha, rTNF-beta), as well as with...

Topics

Antigens
Cell Division
Humans
In Vitro Techniques
Interleukins
Lymphotoxin-alpha
Melanocytes
Phenotype
Recombinant Proteins
Skin Pigmentation
Tumor Necrosis Factor-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7598530
DOI: 10.1007/BF01105076

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7598530-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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