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Article

Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes.

Journal of cell science - 1 Dec 1993

Abdel-Malek Z, Swope V, Collins C, Boissy R, Zhao H, Nordlund J

Abstract excerpt

Human melanocytes from individuals with different skin types, as well as from the skin of the same individual, are heterogeneous in their melanin content. This heterogeneity may be attributed to differences in the activity and expression of the three melanogenic proteins: tyrosinase and tyrosinase-related proteins 1 and 2 (gp75 and DOPAchrome tautomerase, respectively), which in turn are affected by certain...

Topics

Cell Separation
Centrifugation, Density Gradient
Genetic Variation
Humans
Interleukin-1
Intramolecular Oxidoreductases
Isomerases
Melanins
Melanocytes
Membrane Glycoproteins
Monophenol Monooxygenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxidoreductases

Proteins

Skin Pigmentation

Specific Gravity

Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 8126111
DOI: 10.1242/jcs.106.4.1323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8126111-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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