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Article

Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes.

1 Dec 1992

Abstract excerpt

We recently demonstrated that human melanocyte proliferation and differentiation could be stimulated by endothelin (ET) derivatives via a receptor-mediated signal transduction pathway (Yada, Y., Higuchi, K., and Imokawa, G. (1991) J. Biol. Chem. 266, 18352-18357). We show here that the growth factors for human melanocytes are produced and secreted by the surrounding cells, namely human keratinocytes for ET-1 and...

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Identifiers

PMID: 1280264
DOI: 10.1016/s0021-9258(18)35817-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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