Article
[Candidate gene approach in Japanese NIDDM: liver/pancreatic beta cell type glucose transporter (GLUT2)].
Nihon rinsho. Japanese journal of clinical medicine - 1 Oct 1994
Yasuda K, Seino Y
Abstract excerpt
The liver/pancreatic beta cell type glucose transporter (GLUT2) is expressed in the pancreatic beta cell, a glucose carrier with a low affinity for glucose but a high capacity for glucose transport. The expression of GLUT2 in the normal pancreatic islet is increased after exposure to high glucose, while it is decreased in model animal with non-insulin-dependent diabetes mellitus (NIDDM). In Pima Indians, to...
Topics
- Diabetes Mellitus, Type 2
- Humans
- Islets of Langerhans
- Liver
- Monosaccharide Transport Proteins
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
