Article
Molecular scanning of the glycogen synthase and insulin receptor substrate-1 genes in Japanese subjects with non-insulin-dependent diabetes mellitus.
Biochemical and biophysical research communications - 15 Jul 1994
Shimokawa K, Kadowaki H, Sakura H, Otabe S, Hagura R, Kosaka K, Yazaki Y, Akanuma Y, Kadowaki T
Abstract excerpt
We studied a simple tandem repeat DNA polymorphism in the glycogen synthase gene and polymorphisms at codon 513 (Ala-->Pro) and 972 (Gly-->Arg) in the insulin receptor substrate-1 (IRS-1) gene in 197 non-insulin-dependent diabetes mellitus (NIDDM) and 178 control subjects in Japan. Eight alleles...
Topics
- Alanine
- Alleles
- Amino Acid Sequence
- Arginine
- Base Sequence
- Blood Glucose
- DNA Primers
- Diabetes Mellitus, Type 2
- Genotype
- Glycated Hemoglobin
- Glycine
- Glycogen Synthase
- Humans
- Insulin
- Insulin Receptor Substrate Proteins