Article
Variability of the pancreatic islet beta cell/liver (GLUT 2) glucose transporter gene in NIDDM patients.
Diabetologia - 1 Apr 1994
Tanizawa Y, Riggs A C, Chiu K C, Janssen R C, Bell D S, Go R P, Roseman J M, Acton R T, Permutt M A
Abstract excerpt
The purpose of these experiments was to test the hypothesis that impaired glucose-stimulated insulin secretion in NIDDM is due to mutations in the islet beta cell/liver glucose transporter (GLUT 2) gene. Using oligonucleotide primers flanking each of the 11 exons, the structural portion of the ge...
Topics
- Adult
- Alleles
- Amino Acid Sequence
- Base Sequence
- Black People
- DNA Mutational Analysis
- DNA Primers
- Diabetes Mellitus, Type 2
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genetic Variation