Glucokinase gene variations in Japanese-Americans with a family history of NIDDM.

doi:10.2337/diacare.17.12.1480

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Article

Glucokinase gene variations in Japanese-Americans with a family history of NIDDM.

Diabetes care - 1 Dec 1994

Stone L M, Kahn S E, Deeb S S, Fujimoto W Y, Porte D

Abstract excerpt

OBJECTIVE: To determine if sequence variants in the glucokinase (GCK) gene contribute to the high risk of impaired glucose metabolism in Japanese-Americans and whether the gene sequence differs between Japanese-Americans and Caucasians. RESEARCH DESIGN AND METHODS: Forty-seven unrelated Japanese-...

Topics

Adult
Aged
Asian
Diabetes Mellitus, Type 2
Disease Susceptibility
Female
Genetic Variation
Glucokinase
Glucose Tolerance Test
Humans
Islets of Langerhans
Male
Middle Aged
Polymerase Chain Reaction
Prevalence
Promoter Regions, Genetic
Risk Factors

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