An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A.

doi:10.1002/j.1460-2075.1990.tb07404.x

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Article

An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A.

The EMBO journal - 1 Jul 1990

Heyer W D, Rao M R, Erdile L F, Kelly T J, Kolodner R D

Abstract excerpt

Single-stranded DNA binding proteins (SSBs) are known to play a role in DNA replication and recombination in prokaryotes. An SSB was previously purified from the yeast Saccharomyces cerevisiae. This SSB stimulated the activity of a cognate strand exchange protein (SEP1) in vitro suggesting a role in recombination. We have cloned and functionally analyzed the gene encoding this protein. DNA sequencing of the...

Topics

Amino Acid Sequence
Base Sequence
Chromosomes, Fungal
Cloning, Molecular
Crosses, Genetic
DNA-Binding Proteins
Fungal Proteins
Gene Library
Genes, Fungal
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macromolecular Substances

Molecular Sequence Data

Molecular Weight

Plasmids

Replication Protein A

Restriction Mapping

Ribosomal Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 2192864
DOI: 10.1002/j.1460-2075.1990.tb07404.x
PMCID: PMC551959

Genes

RPA1
SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2192864-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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