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Article

An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A.

The EMBO journal - 1 Jul 1990

Heyer W D, Rao M R, Erdile L F, Kelly T J, Kolodner R D

Abstract excerpt

Single-stranded DNA binding proteins (SSBs) are known to play a role in DNA replication and recombination in prokaryotes. An SSB was previously purified from the yeast Saccharomyces cerevisiae. This SSB stimulated the activity of a cognate strand exchange protein (SEP1) in vitro suggesting a role in recombination. We have cloned and functionally analyzed the gene encoding this protein. DNA sequencing of the...

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Source

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Identifiers

PMID: 2192864
DOI: 10.1002/j.1460-2075.1990.tb07404.x
PMCID: PMC551959

Genes

RPA1
SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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